Events Calendar View

• NanoSEC Seminar Oct 22, 2010

  Rational Design Protein-based MRI Contrast Agents (ProCAs) with High Relaxivity and Target Capability to different types of Biomarkers

  

  Guest: Jenny J. Yang, Ph.D., Departments of Chemistry, Center for Drug Design and Advanced Biotechnology Georgia State University
  Friday, October 22, 2010 4:00 pm - 5:00 pm
  Location: Riverbend Research South Laboratory Auditorium

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  We have developed a new class of protein-based MRI contrast agent (ProCA) by de novo design of Gd3+ binding site(s) into a stable host protein with significantly improved MRI relaxivity at medical application field strengths. Designed proteins show strong Gd3+ affinity and selectivity over excess Ca2+ and other metal ions and a significant improvement in in vivo dose efficiency over clinically approved small molecule based contrast agents such as DTPA. These design ProCAs also exhibit a large improvement in blood retention time and pharmokinetics with excellent enhancement in angiography. Furthermore, we have successfully designed targeted MRI contrast agents to specifically recognize various biomarkers such as gastric release peptide receptors and HER2/EGFR overexpressed in different types of cancers and cell types without using antibodies. These developed targeting MRI contrast agent exhibit strong receptor-specific MRI enhancement both in tumor cells and xenograft mice models with desirable penetration of tissue and the endothelial boundary with applications in monitoring the level of expression and distribution of biomarkers in vivo and examining the response upon treatment by the targeted therapeutics.

• CSP Lunch Seminar Oct 26, 2010

  Wang-Landau Simulations of Thermodynamic Behavior in Homopolymer Systems

  

  Guest: Daniel Seaton, University of Georgia, Department of Physics and Astronomy
  Tuesday, October 26, 2010 12:30 pm - 1:30 pm
  Location: CSP Conference Room (322)

  iCal
• NanoSEC Seminar Oct 29, 2010

  Advanced Electron Microscopy at CAUR

  

  Guest: Jianguo Fan, Center for Advanced Ultrastructural Research, Department of Physics and Astronomy, Department of Geology, The University of Georgia
  Friday, October 29, 2010 4:00 pm - 5:00 pm
  Location: Riverbend Research South Laboratory Auditorium

  iCal

  Electron microscopy has become a key element in many research activities. In this talk, I will give an introduction to various microscopy instruments and techniques at CAUR (Center for Advanced Ultrastructural Research) for your research needs. A few examples will be illustrated.

• CSP Lunch Seminar Nov 2, 2010

  Heisenberg model with competing interactions

  

  Guest: Paulo Martins
  Tuesday, November 2, 2010 12:30 pm - 1:30 pm
  Location: CSP Conference Room (322)

  iCal
• Departmental Colloquium Nov 4, 2010

  Postponed

  

  Guest: Dr. Rodney Canfield, University of Georgia Department of Computer Science
  Thursday, November 4, 2010 4:00 pm - 5:00 pm
  Location: Physics 202

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• CSP Lunch Seminar Nov 9, 2010

  Ab-initio modeling of complex metal hydrides for hydrogen storage purposes

  

  Guest: Feng Zhang, Georgia Tech
  Tuesday, November 9, 2010 12:30 pm - 1:30 pm
  Location: CSP Conference Room (322)

  iCal

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