Mesenchymal Stem Cells (MSCs) are promising therapeutics for inflammatory diseases and musculoskeletal regeneration; but challenges in identifying highly potent cells and evaluating their in vivo behavior have slowed clinical translation. Dr. Mortensen’s research program develops advanced intravital 2 photon imaging strategies including laser ablation, adaptive optics correction, and super-resolution imaging to probe mesenchymal stem cell (MSC) therapies for inflammation and bone disease and the study of regenerative processes.