Events Calendar View
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Observatory Open House
Feb 24, 2012
Observatory Open House
The Department of Physics and Astronomy would like to invite the public to join them for a evening to view the night sky at the department observatory. The observatory is located at the top of the Physics building. In case of inclement weather, there will be a talk. See the UGA Observatory Schedule for more information. -
Departmental Colloquium
Mar 1, 2012
TBA
TBA
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NanoSEC Seminar
Mar 2, 2012
Gene Delivery for Protein Drug Discovery and Gene Therapy
Discovery of protein drugs has been one of the major focuses in biotechnology. Conventional approach involves expression of the candidate protein in cultured cells, isolation of the expressed protein from cell extracts or medium, and assessment of its therapeutic activity by injecting the protein into an animal. This talk will describe a new approach toward identification of a therapeutic protein or for protein drug discovery. The strategy involves the development of gene delivery method to allow expression of the candidate gene directly in animals bearing a disease, thereby bypassing the need for preparation and administration of protein into animals. The talk will center around recent progress in development of synthetic carriers and physical method for gene delivery. The advantage and disadvantages of the delivery
systems, and their potential for gene therapy will also be discussed. -
CSP Lunch Seminar
Mar 6, 2012
Applications of Radiation Hydrodynamics in Inertial Confinement Fusion
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Departmental Colloquium
Mar 8, 2012
Plasmonics and Metamaterials for Extreme Light Manipulation
Plasmonics has become a very important branch in nano optics, focusing on the new physical phenomena and exciting applications associated with metallic nanostructures. Plasmonics allows us to concentrate, guide, and manipulate light at the deep subwavelength scale, promising enhanced light-matter interaction, sub-diffraction-limited imaging, efficient solar energy harvesting, and ultrasensitive biomedical detection. Furthermore, the assembly of metallic nanostructures can be used to construct optical metamaterials with exotic properties and functionalities, including artificial magnetism, negative refraction, and invisibility cloak.
In this talk, after the introduction of plasmonics and metamaterials, I will present some of my recent work on extreme light manipulation utilizing the two schemes. First, I will describe the design and demonstration of the first optical negative refraction in bulk metamaterials made of metallic nanowires, which exhibit low-loss, broad-band and all-angle advantages. Second, I will introduce a new concept of transformational plasmonics to mold near-field plasmon waves at the metal-dielectric interface in a prescribed manner. For instance, this approach enables surface plasmon waves to travel smoothly at uneven surfaces, where surface plasmons would normally suffer considerable scattering losses. Some plasmonic devices, such as a plasmonic bend and a plasmonic Luneburg lens, will also be presented. Finally, I will demonstrate a fully subwavelength and efficient nano-plasmonic source for unidirectional generation of surface plasmons, which is a key building block for the next generation of ultra-fast and ultra-compact integrated optical circuits. By tailoring the relative phase at resonance and the separation between two magnetic metamaterial resonators, surface plasmons can be steered to predominantly propagate along one specific direction. Such a device not only serves as a highly directional surface plasmon generator, but also could be useful for surface-plasmon-based nonlinear applications, active modulation and wireless communication.
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NanoSEC Seminar
Mar 9, 2012
Overcoming Pancreatic Cancer Chemoresistance as a Therapeutic Challenge
Gemcitabine, a nucleoside analog drug, is the current standard of care for the treatment of pancreatic cancer. Its effects are suboptimal partly due to cellular mechanisms limiting its transport, activation, and overall efficacy. Nonetheless, novel therapeutic approaches are presently under study to circumvent gemcitabine resistance in pancreatic cancer. Specifically, microRNA (miRNA) control of gemcitabine chemoresistance will be discussed. With these new approaches come additional challenges to be addressed. The presentation summarizes the determinants of chemoresistance in the gemcitabine cytotoxicity pathways, provides an overview of miRNA investigational approaches for
overcoming chemoresistance, and discusses new challenges presented. Understanding the future directions of the field may assist in the successful development of novel treatment strategies for enhancing chemotherapeutic efficacy in pancreatic cancer.
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